NEA Mandates and Structures


High-level Group on Low Dose Research (HLG-LDR)

Chair(s): Dominique LAURIER, France
Secretary:  George VARDULAKIS
(george.vardulakis@oecd-nea.org)
Vice-Chair(s): Vinita CHAUHAN, Canada
Marie-Claude GREGOIRE, Canada
Nicholas PRIEST, Canada
Olivier ARMANT, France
Dmitry KLOKOV, France
Paul LOCKE, United States
Member(s):All NEA member countries*
Russia (Suspended*)
*Russian Federation suspended pursuant to a decision of the OECD Council.
Full participant(s): European Commission
Under the NEA Statute
Observer(s)(International Organisation): International Atomic Energy Agency (IAEA)
By agreement
Date of creation:01 June 2021
End of mandate:31 May 2027

Mandate (Document reference):

  • Summary Record of the 76th Plenary meeting of the Committee on Radiological Protection and Public Health (CRPPH) on 10-12 April 2018 [NEA/CRPPH(2018)1]
  • Summary Record of the 77th plenary meeting of the Committee on Radiological Protection and Public Health (CRPPH) on 27-29 March 2019 [NEA/CRPPH(2019)4/FINAL]
  • Summary Record of the 78th plenary meeting of the Committee on Radiological Protection and Public Health (CRPPH) on 9-11 September 2020 [NEA/CRPPH(2020)5]
  • Mandate of the High-Level Group on Low Dose Research (HLG-LDR) [NEA/CRPPH(2020)7]
  • Summary Record, Agreements and Decisions of the 81st Meeting of the Committee on Radiological Protection and Public Health, 4-6 April 2023 [NEA/CRPPH(2023)6/FINAL]
  • Summary Record, Agreements and Decisions of the 7th Meeting of the High-Level Group on Low Dose Research, 27-28 June 2023 [NEA/CRPPH/HLGLDR(2024)1]
  • Mandate of the High-level Group on Low Dose Research (HLG-LDR) [NEA/CRPPH/HLGLDR(2024)2/FINAL]

Mandate (Document extract):

Extract of document NEA/CRPPH/HLGLDR(2024)2/FINAL

Mandate

Background

The importance of low-dose/low-dose rate research is widely recognised, and it is pursued by multiple publicly funded organisations (e.g. specialised government agencies, national research foundations, the European Commission). There are efforts made on national and regional level to collaborate and co-ordinate the broad range of research activities already done and ongoing across the globe. To leverage these efforts, it is important to strengthen the worldwide network of low-dose/low-dose rate effect research community, identify/improve funding opportunities to promote research activities and implementing organisations to provide meta-coordination on a global level.

The NEA Committee on Radiological Protection and Public Health (CRPPH) at its 77th meeting recommended that an ad-hoc High-level Group on Low-Dose Research (HLG-LDR) should be created to examine the situation and to propose a way forward. An initial group of research funding and implementing organisations developed a vision and a broad approach to facilitate the identification of ongoing and planned research programmes to be co‑ordinated. The CRPPH agreed at its 78th meeting to establish HLG-LDR as a level-two NEA body to address global low dose research co-ordination.

During its 81st meeting, the CRPPH acknowledged the significant achievements of the HLG-LDR, including the creation of the Global Register of Low Dose research projects, the publication of the first of the kind Adverse Outcome Pathways related to radiation exposure, and recognised the escalating global interest in low-dose areas within the broader scope of the nuclear industry and medical applications of ionising radiation. In this context, a three-year extension of the HLG-LDR mandate was approved in principle at both the 81st meeting of the CRPPH in April 2023 and the 7th plenary meeting of the HLG-LDR in June 2023.

Scope

The HLG-LDR will support radiological protection policy, regulation, and implementation choices by improving the effectiveness and efficiency of research through global networking for the co-ordination of ongoing and future low-dose research projects. This involves developing innovative tools for information sharing and dissemination, identifying and addressing research gaps in low-dose effects, and fostering improved communication with stakeholders. These efforts aim to streamline worldwide research coordination and ensure transparent communication of research objectives and outcomes to decision makers and other relevant stakeholders.

Objectives

The specific objective of the HLG-LDR is to maintain and enhance a global network that facilitates collaboration among ongoing and planned low-dose / low-dose rate ionising radiation research programmes and encourages the collective sharing of information and resources.

To achieve this, the HLG-LDR will:

i) Accelerate the outreach of the radiological protection community, with a focus on policy and decision makers, in addition to researchers; Develop initiatives to bring closer radiation and chemical communities.

ii) Educate, train and inform the next generation of risk assessors using a variety of approaches.

iii) Develop coordination of existing biobanks (animal and human) and initiate a community of practice.

iv) Pursue the improvement and dissemination of the Global Register of Low-Dose Research Projects worldwide and develop a long-term strategy for its management.

v) In close interaction with the OECD Adverse Outcome Pathway (AOP) programme, further develop radiation related AOPs, communicate its benefits and challenges to stakeholders, showcase its usefulness through case studies, and improve the review/endorsement process.

Working methods

The HLG-LDR will conduct its activities through plenary meetings (once a year, and more, as needed, upon decision of the working party and taking into account the Secretariat’s resources) and through the organisation of seminars and workshops as agreed by the members of the HLG‑LDR.

The HLG-LDR will elect a Chair and Vice-Chair(s) among its members (Bureau). The Bureau co-ordinates and facilitates the work of the HG-LDR. The Bureau would preferably meet twice a year, with one meeting normally held in conjunction with the annual plenary meeting.

The HLG-LDR reports to the CRPPH at least once per year.

Additionally, the HLG-LDR

i) identifies resources and schedules its activities. Activities of the HLG-LDR will be financed at least partially by voluntary contributions;

ii) forms ad hoc bodies to work on specific projects and to organise workshops, as appropriate; and

iii) creates topical groups for more task oriented work in consultation with the CRPPH.

Membership

The HLG-LDR delegates shall be composed of CRPPH nominated representatives from NEA member countries. Delegates shall include a diverse range of senior specialists who have considerable experience and knowledge in the area of low-dose/low-dose rate research activities. This representation will be wide-ranging and include research funding and implementing specialists. 

Interactions

The HLG-LDR will interact as appropriate with other NEA standing technical committees, OECD Directorates and national organisations of NEA member countries.

Where appropriate, experts of relevant international organisations or international fora may be invited to attend the meetings and contribute to the HLG-LDR’s work. Such relevant organisations are, for example:

  • the International Commission on Radiological Protection (ICRP);
  • the United Nations Scientific Committee on the Effects on Atomic Radiation (UNSCEAR);
  • the World Health Organisation (WHO);
  • Research Platforms or Associations [such as European platforms e.g. MELODI and the European Radioecology Alliance]; the International Dose Effect Alliance (IDEA); the Japanese Planning and Acting Network for Low Dose Radiation Research (PLANET); the Canadian Organization on Health Effects from Radiation Exposure (COHERE)];
  • the association Heads of the European Radiological Protection Competent Authorities (HERCA) and the US National Council on Radiation Protection and Measurements (NCRP).

The principles underpinning these interactions are: identifying synergies, co-ordinating efforts and avoiding duplication of work optimising resources.

Deliverables

The HLG-LDR, with the support of the Secretariat, will produce reports and other documents deemed appropriate by its members and the CRPPH to improve the dissemination of information regarding low-dose/low-dose rate research co-ordination.

For this mandate, the expected deliverables are as follows:

  • Proceedings of one or two workshops on low-dose research coordination initiatives;
  • Publications of radiation-related adverse outcome pathways;
  • Improved version of the Global Register of Low-Dose Research Projects;
  • Education and training materials (e.g. infographics, videos, tutorials).